Celiac Disease: Testing & History

Just saw this on "Real Orange" on PBS: (you know most of this probably, but I wasn't aware of the blood tests or its history...)

An interview with Dr. Glenn Madokoro of Hoag Hospital.

Says it is highly undiagnosed: most people don't know they have it (every 1 in 133) — which is better than saying most people think they have it but really don't (overdiagnosed)…like ADHD hype.

Gluten Sensitivity comes in 3 forms or causes: (=wheat protein or a fragment of gluten called Gliadin)
1) Celiac (auto-immune disease)

2) Allergy (Immunoglobulin Reaction)
3) Idiopathic Intolerance (fancy way of saying "of unknown cause")

Diagnosis can be done with a simple Blood Test (I didn't know that):
(If preliminary positive, then Small Intestine Biopsy should be done)

"tTG,IgA" & "AGA,IgG/IgA" — see explanations here:
Celiac Disease Tests At A Glance
[this site is also a great resourse for information on other blood tests and labs: http://www.labtestsonline.org]
Antibody Blood Tests pamphlet

4% of those with Irritable Bowel symptoms actually have some form of Celiac.

Treatment
95% thru elimination of gluten in diet
5% require additional immuno-suppressive agents (as well as deeper look for hidden gluten and/or other disease)


Causes Small Intestinal Damage and problems such as:
- Osteoporosis
- Miscarriages & Infertility (!!!)
- Weight Loss (if only, right?)
- Vitamin Deficiencies
- Mal Absorption
- "Intolerance" form can cause Neuorological Conditions (over 600 diseases, including: SLEEP DISORDERS, Alzheimers, Tourettes, Epilepsy, AUTISM, as well as, Huntingtons, Muscular Dystrophy, Spina Bifida, Parkinson, stroke)  
the term "celiac" is over 2000 years old, first diagnosed (labeled) by a Greek physician who named it after the word for "abdomen," koelia.  He didn't understand what caused it.

Wasn't until WWII that Gluten was identified as the trigger following a shortage of bread in the Netherlands after World War II, which caused the death rate of children affected by celiac disease to drop from 35% to zero; and then rise once bread was available again.

The FIRST elimination diet!

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